- 1 What is Meldonium?
- 2 Meldonium uses
- 3 Meldonium: Buy in Canada
- 4 Meldonium (Mildronate) Indications
- 5 Meldonium (Mildronate) dosage
- 6 Meldonium 250 mg and 500 mg prices for sale online in US and UK
- 7 Mildronate side effects
- 8 How to buy Meldonium ( Mildronate) online? Meldonium capsules cost
- 9 How does Meldonium work?
What is Meldonium?
Meldonium is better known as Mildronate – a drug that improves metabolism and energy metabolism in tissues.
Meldonium (Mildronat) was developed in 1975 by Professor Ivar Kalvins, now head of the Department of Medical Chemistry of the Latvian Institute in Riga.
He was looking for a substance in the body, whose resources are depleted during systematic overloads. A gamma-butyrobetaine substance was detected. It was transformed for convenient storage and use, so it turned out meldonium.
What is mildronate prescribed for?
The drug Mildronate contributes to improving performance, endurance, reducing the symptoms of overexertion – for the sake of these effects, almost all athletes in Russia and the CIS countries took mildronate, and amateur athletes still continue to take this drug. In 2016, Meldonium became even more popular with amateurs than before. The logic here is simple: once the drug is banned, it means it works!
According to the creator of the drug, Professor Ivar Kalvinsha, there are no clinical studies showing that Meldonium will increase strength, endurance, speed, and so on. And this means that there are no medical grounds for prohibiting the use of the drug.
Meldonium protects the cells of the heart during high-intensity work. When working on a high pulse, there is a lack of oxygen and an increased risk of ischemic heart disease.
Thanks to Meldonium, the athlete will not become faster, stronger and more enduring. The effect of Meldonium is to improve the tolerability of training, the body perceives large loads without harm to health and is better restored.
There are many proven ways to significantly increase strength and endurance with the help of drugs (mostly prohibited), but Meldonium does not apply to such drugs. Rather, it will give the opposite effect during the competition, not allowing to work “for wear”.
Meldonium has the following effect:
– eliminates the symptoms of overstrain – both mental and physical;
– protects the heart;
– increases myocardial contractility;
– tones up the central nervous system;
– when alcoholism eliminates violations in the work of the central nervous system, if the patient refused to drink alcohol;
– protects the integrity of the walls of blood vessels;
– reduces the oxygen demand of myocardial cells;
– reduces the effects of oxygen starvation;
– stimulates tissue and humoral immunity, increases resistance to infections.
Meldonium: Buy in Canada
How to buy Meldonium in Canada cheap?
Any medicine you need can be purchased at a Canadian city pharmacy, but this may be a bit more expensive than many online pharmacies.
Many people have already seen that buying Meldonium at an online pharmacy is cheaper. An ordinary Canadian city pharmacy has a lot of expenses – it is the rent of retail space and the payment of salaries to the staff – all of these costs are included in the price of Meldonium. In addition, an ordinary Canadian pharmacy buys the drug from a wholesale supplier, and he already sells it with a substantial markup, including driver, logistics, manager and other expenses.
In general, when you buy the drug Meldonium in a regular pharmacy in Canada, its price includes the premium of the wholesale supplier and the distribution network. If the place of purchase is an online pharmacy, then the wholesaler is the intermediary.
Based on this, many buyers begin to buy the drugs they need in proven and reliable online pharmacies. Online pharmacies can be Canadian, Indian or other. But one thing remains unchanged – the prices of Meldonium and other drugs in these pharmacies are much lower, the delivery of drugs is carried out worldwide, the purchases are completely anonymous.
Meldonium (Mildronate) Indications
Meldonium, prescribed for myocardial infarction, inhibits the development of tissue necrosis in the heart, so that the dying zone expands more slowly, accelerating the recovery of the patient.
The drug is well absorbed from the digestive tract if it is prescribed in dosage forms for internal administration. The maximum concentration is observed after 60-120 minutes after use.
Bioavailability is 78%. In the body it decomposes into two metabolites, which are excreted by the kidneys.
The doctor appoints Meldonium as part of a comprehensive treatment for such diseases:
- an abstinence syndrome in patients with chronic alcoholism;
- rehabilitation after surgery;
- impaired cerebral circulation of acute and chronic form as a consequence of strokes and cerebrovascular insufficiency;
- impairment of working capacity, significant physical exertion, including those involved in sports.
Meldonium is effective in ocular diseases (parabulbar injection is prescribed):
- impaired blood flow of the eye retina in the acute phase;
- hemophthalmus, when blood enters the vitreous or into the surrounding space;
- the formation of thrombi in the central vein of the retina or in branching vessels;
- retinopathy, including those arising as a consequence of diabetes and hypertension.
Meldonium (Mildronate) dosage
Athletes are prescribed Meldonium in combination with other drugs on an individual basis. The same if the application of the remedy is caused by illness. Such daily doses are established.
Patients after the operation, during overloads, during the rehabilitation period:
- Capsules inside by 250 mg from 2 to 4 times, intramuscularly (in / m) – by 500 mg to 2 times.
- Duration of therapy – from 10 to 14 days, therapy is allowed to repeat after 14-21 days.
- For stable angina, the first 3-4 days are prescribed by 250 mg 3 times. Then take inside twice a week at a daily dosage of 250 mg 3 times. The duration of therapy is from 4 to 6 weeks.
- For the unstable form of angina and myocardial infarction, Meldonium is used intravenously in a jet method, 500 mg or 1 g once a day. In the future, appoint inwards: 3-4 days – 250 mg 2 times, then 2 days a week for 250 mg 3 times a day.
- For chronic heart failure, the drug is administered intravenously in a jet method every day at a dose of 500-1000 mg or replaced by intramuscular injection of 500 mg to 2 times a day. After 10-14 days of treatment, the patient is transferred to 500 mg capsules, which he takes 1 time in the morning. The course of treatment is from 4 to 6 weeks.
- For cardialgia associated with dyshormonal dystrophy of the myocardium, the drug is administered iv by a jet method once a day for 500-1000 mg or IM to 2 times a day for 500 mg. After 10-14 days, a capsular form is prescribed For 250 mg in the morning and in the evening, the treatment continues for another 12 days.
- For disturbed cerebral circulation, Meldonium is recommended during an exacerbation period of 500 mg once a day for 10 days, then in capsule form – 500 mg daily for 14-21 days. In the chronic form of circulatory disorders of the brain, a course of treatment of 14-21 days is prescribed.
Solution for injection is injected intramuscularly by 500 mg once a day or prescribed by mouth at 250 mg (the frequency depends on the severity of the patient’s condition).
An abstinence syndrome requires a course of therapy with Meldonium for 7-10 days. Then the patient is shown a four-fold intake of the drug during the day for 500 mg orally or twice – intravenously.
In vascular diseases of the fundus, dystrophy of the retina, Meldonium is prescribed retrobulbarno and subconjunctivally 50 mg for 10 days.
Meldonium 250 mg and 500 mg prices for sale online in US and UK
Meldonium is available in several dosage forms:
- Injection for 100 mg / ml, 5 ml ampoules, 5 or 10 ampoules in the package;
- Solution for injection with a concentration of 500 mg / 5 ml, in the package from 5 to 100 ampoules;
- Capsules 250, 500 mg in a blister, 3, 6 packs in a cardboard bundle;
How much does Meldonium cost in US and UK online pharmacies?
Further in the table we will show you the average cost of the drug Meldonium in well-known online pharmacies in the US and the UK:
|Meldonium||500 mg||250 mg|
Mildronate side effects
Meldonium usually has a mild effect on the body. But patients rarely developed such side effects:
- In the heart and blood vessels – tachycardia (a symptom manifested in violation of the heart rhythm), changes in blood pressure;
- In the central nervous system – psychomotor agitation;
- In the digestive tract – symptoms of digestive disorders;
- Immune system – allergic reactions, rash, swelling, redness of the skin.
How to buy Meldonium ( Mildronate) online? Meldonium capsules cost
You can buy Meldonium in the online pharmacy of our partner:
Below are the prices for the preparation of meldonium 500 mg and 250 mg.
Meldonium 500 mg prices
40 caps – $49.20 ($1.23 per capsule)
60 caps – $65.50 ($1.09 per capsule)
90 caps – $89.94 ($1.00 per capsule)
120 caps – $114.39 ($0.95 per capsule)
180 caps – $163.28 ($0.91 per capsule)
360 caps – $309.96 ($0.86 per capsule)
Meldonium 250 mg prices
40 caps – $46.00 ($1.15 per capsule)
60 caps – $61.24 ($1.02 per capsule)
90 caps – $84.09 ($0.93 per capsule)
120 caps – $106.95 ($0.89 per capsule)
180 caps – $152.66 ($0.85 per capsule)
360 caps – $289.80 ($0.81 per capsule)
To order meldonium online click the link below:
How does Meldonium work?
Glycogen and fats are used for energy production. Glycogen is a more “beneficial” fuel for the body, because it does not need to be recycled. Mildronate inhibits the use of fat and activates the use of glycogen. This is especially important with a lack of oxygen (a very high intensity load).
With a lack of oxygen, fats do not have time to fully oxidize, harmful by-products are formed. Mildronate prevents these processes. Less energy is produced from glycogen, but less oxygen is also required. It is logical that this does not improve the strength and power of the body, but it does not allow the cells to die off at the time of oxygen starvation. Simply put – it is the survival of the body, by reducing power.
This explains the interest of the military in the Meldonium preparation. This drug helps to cope with the task of survival without harm to the heart.