- 1 What is Ciprofloxacin (Cipro)?
- 2 What is Ciprofloxacin 500 mg tablets used for?
- 3 Another name for Ciprofloxacin
- 4 Cipro (Ciprofloxacin) cost
- 5 Ciprofloxacin mechanism of action. How does Ciprofloxacin work?
- 6 Ciprofloxacin dosage
- 7 Ciprofloxacin prescription
- 8 Ciprofloxacin uses. Tablet form. What does Cipro treat?
- 9 Is Cipro a strong antibiotic?
- 10 Cipro indications. What does Ciprofloxacin treat?
- 11 Ciprofloxacin (Cipro) alternatives
- 12 When to take Cipro for travelers’ diarrhea?
- 13 Is Cipro good for tooth infection?
What is Ciprofloxacin (Cipro)?
The drug is available in pill form. The main active ingredient of the drug is ciprofloxacin. Additional components are microcrystalline cellulose, potato starch, magnesium stearate, polysorbate.
Dr. Brigitte Mueller-Morel, MD: Ciprofloxacin is active against pathogens of gram-positive and gram-negative nature. The effect of the drug lies in its ability to exert an overwhelming effect on topoisomerases that occur during the life cycle of bacteria.
The active components of the drug are absorbed by the organs of the gastrointestinal tract, the upper intestines. The maximum concentration in the plasma of the main substance is reached within a few hours after taking the medicine. Excreted from the body by the kidneys, along with urine, part goes through the intestine with feces.
What is Ciprofloxacin 500 mg tablets used for?
Ciprofloxacin 500 is prescribed in the treatment of the following diseases:
- a number of infections of the respiratory system;
- infectious diseases of the eyes and ears;
- infections of the genitourinary system;
- diseases of the skin;
- disorders of the articular and bone tissue;
Ciprofloxacin is effective for prophylactic use when a patient has a weakened immune system, against which there is a high risk of attaching infections. This tool is used in complex therapy, if the patient takes drugs from the group of immunosuppressants for a long time.
Is it possible to take Ciprofloxacin (Cipro) for diabetes?
Ciprofloxacin can be taken by patients with diabetes mellitus, but in this case it is necessary to adjust the dosage of anti-diabetic drugs.
Another name for Ciprofloxacin
Another name for Ciprofloxacin is Cipro.
International non-proprietary name: Ciprofloxacin
Dosage Form: 500 mg coated tablets
Cipro (Ciprofloxacin) cost
How much is Cipro (Ciprofloxacin)?
The cost depends on the amount of the main substance and the form of release. Price ranges from $ 40 to $ 365.
Cipro 250 mg:
90 pills – $40.86;
360 pills – $90.
Cipro 500 mg:
60 pills – $45;
360 pills – $120.
Cipro 750 mg:
30 pills – $60;
360 pills – $365.
Ciprofloxacin mechanism of action. How does Ciprofloxacin work?
Ciprofloxacin is an antibiotic that has a bactericidal effect against the widest range of pathogenic microorganisms. It does not slow down or suspend the development and reproduction of the objects of the micro world, as bacteriostatic preparations do, but completely destroys the bacteria, causing their death and subsequent elimination from the body.
The mechanism of action of this antibiotic is based on the inhibition of bacterial DNA gyrase, the enzyme responsible for doubling DNA, without which the process of protein synthesis is inconceivable.
How to take Ciprofloxacin?
The average recommended dosage of the drug is 250 and 500 mg. But the dosage and duration of the therapeutic course are selected individually, depending on the severity of the clinical case and the intensity of the symptomatic picture.
The following schemes are common:
1. 500 mg once a day. It is prescribed for the prevention of postoperative complications, with mild gonorrhea or chlamydia, with non-purulent otitis.
2. 1000 mg once a day should be taken in the treatment of uncomplicated prostatitis.
3. 500-1000 mg once or the dose is divided into 2 doses. This dosage is indicated for cystitis and other inflammations of the lower urinary tract.
4. 1000-1500 mg per day (once or at intervals of 12 hours). This dose is necessary for severe skin infections. Reception of the tablet form is combined with the external application of ointment, which should contain ciprofloxacin hydrochloride monohydrate or its equivalent.
5. Infectious diseases of the kidneys, occurring in uncomplicated form: 250 mg, 500 mg is allowed. Reception is carried out 2 times a day.
6. Infections of the lower organs of the respiratory system of the average intensity of the clinical picture – 250 mg, with a severe course of the disease – 500 mg.
7. Gonorrhea – dosage ranges from 250 to 500 mg, with an intense symptomatic picture, an increase up to 750 mg is allowed, but only for 1-2 days at the beginning of the therapeutic course.
8. Dosage in the treatment of gynecological diseases, colitis in severe cases, prostatitis and other diseases of the urogenital organs, accompanied by an increase in body temperature indicators, the drug is taken twice a day, the dosage is 500 mg.
9. If a person has prolonged diarrhea, for the treatment of which intestinal antiseptics are needed, Ciprofloxacin is applied at a dosage of 250 mg twice a day.
- Infectious diseases of the upper respiratory system – 400 mg three times a day.
- Sinusitis in chronic form, otitis purulent and external type, malignant – 400 mg three times a day.
- Other infectious diseases, regardless of the location of the pathogen – 400 mg 2-3 times a day.
Treatment of children with cystic fibrosis – the dosage is calculated according to the scheme: 10 mg of the main substance per kilogram of body weight, three times a day, the amount of the drug for 1 time should not exceed 400 mg.
Complicated during pyelonephritis – 15 mg per kilogram of body weight, twice a day.
Therapy of organs of vision and ears in the presence of bacteria is carried out according to the following scheme – the average dosage is 1-2 drops, apply up to 4 times per day.
If the patient, in addition to Ciprofloxacin, was prescribed other drops, they should be used in a complex manner, the time interval between the use of drugs should be at least 15-20 minutes.
By definition, a prescription is a doctor’s request, provided to the pharmacy in writing for the issuance of a specific drug to a patient.
Dr. Brigitte Mueller-Morel, MD: In such a request, the specialist indicates all the important data that allows the pharmacist to determine in what form the drug is required, what its dosage is, and how often it is necessary to use the prescribed drug.
When prescribing Ciprofloxacin, the attending physician writes a prescription in Latin, since only he has the right to make a request to the pharmacy to distribute the drug to the patient, ensuring the accuracy of the prescribed dosage, schedule of administration and the duration of the course of treatment.
Recipe design rules
It is only a practicing qualified person who is authorized to write a prescription to receive a specific drug at a pharmacy. To process this document, certified not only by the signature of the attending physician, but also by his personal stamp, it is necessary to follow the existing rules and use the Latin language.
Abbreviations written in Latin mean:
Rp (Recipe) – “take it”.
D.T.D (Da tales doses) – “give so many doses“.
Signa – “label“.
Sol (Solutio) – “solution”.
Tab (Tabulettae) – “tablets”.
(ampullis) – “in ampoules”.
Flak (flakonis) – “in a bottle”.
First of all, the doctor writes Rp: what does “take” mean, and then also the name of the drug indicates strictly in Latin. In this case, Ciprofloxacin. After that, you must specify the dosage chosen by the doctor.
The next checkout item for the pharmacy is D.t.d. (“give a certain number of doses”). After the “No.” sign, the specialist indicates the number of prescribed doses of the drug. If it is a solution for injection or eye drops, you should specify the number of ampoules or the volume of the vial. When prescribing the drug in pill form, the number of tablets after the “No.” mark is indicated in the prescription in the prescription. The Latin letter S (Sigma) indicates the rules for taking the medicine (dosing regimen and schedule of administration).
An example of Ciprofloxacin prescription for tablets:
Rp: Ciprofloxacini 0.25D.t.d: N 20 in tab.S: 2 tablets 2 times a day.
An example of Ciprofloxacin prescription for injection:
In order to purchase a Ciprofloxacin solution for intravenous administration in a pharmacy, you must provide a prescription written out and certified by your doctor. Such an appeal to the pharmacy to dispense drugs should look like this:
Rp: Solutio Ciprofloxacini 0,2% – 50 ml. D.t.d. No. 2 S. Introduce intravenously slowly, prediluting in 100 ml of isotonic sodium chloride solution. The course of treatment is 7-10 days.
Ciprofloxacin uses. Tablet form. What does Cipro treat?
In order to write a prescription for the purchase of Ciprofloxacin tablets, the doctor must confirm the preliminary diagnosis and make sure that the patient has such illnesses as:
Severe infections of the organs of hearing;
- Inflammatory processes in the airways;
- Infectious and inflammatory diseases of the abdominal cavity, digestive organs;
- Lesions of the articular apparatus and bone tissue;
- Condition after suffering a complicated surgical intervention;
- Infections of soft tissue and dermis;
- Bronchopulmonary infection;
- Cystic fibrosis;
- Infectious diseases of the urinary tract and kidney damage;
- The inflammatory process in the lower respiratory tract;
- Pneumococcal infection;
All of these diseases require timely, high-quality and adequate treatment. You can achieve a positive result by prescribing a tablet for the patient Ciprofloxacin.
Each tablet contains 250 or 500 mg of active ingredient, and only a highly qualified doctor is able to choose the desired dosage.
Directing the patient to the pharmacy to get the drug, the specialist writes him a prescription that looks like this:
Rp: Ciprofloxacinum 0.5.
D.t.d. No. 5
S. 1 tablet 2 r / d. take after meals for 5 days.
The duration of the course of treatment and the daily dose of the drug are set in accordance with the instructions given in the accompanying instructions:
1. For infections of the upper and lower respiratory tract, the duration of Ciprofloxacin in tablet form is from 1 week to 14 days. The dosage is determined in accordance with the severity of the disease and is 500 or 750 mg, which are taken twice a day.
2. A daily dose of 750 mg of Ciprofloxacin is prescribed to older patients suffering from diseases that affect the organs of hearing (purulent otitis, chronic inflammation of the maxillary sinuses in the acute stage). For children, a daily intake of no more than 500 mg of the drug is recommended. The average duration of a course of therapy is 2 weeks.
Despite the high efficacy of Ciprofloxacin, there are contraindications for its use in the form of tablets. This is the early childhood or elderly (over 65 years) patient’s age, hypersensitivity and individual intolerance to the active substance, state of pregnancy and lactation.
Proper registration of the prescription (doctor’s request to the pharmacy to issue the drug to the patient) allows the patient to receive the right medication without errors and delays and start therapeutic measures in a timely manner.
Is Cipro a strong antibiotic?
Ciprofloxacin helps with infections caused by bacterial microflora. Antibiotic is used in urology, gynecology, skin inflammation, diseases of the ENT organs and other diseases caused by bacteria. But this drug should not be considered a universal remedy and should be drunk at the first signs of indisposition – this can be harmful to health. Let’s see what is said in the annotations to the drug.
The antibiotic Ciprofloxacin has a wide spectrum of action and its active ingredient is ciprofloxacin hydrochloride monohydrate.
- gram-positive bacteria (staphylococcus, streptococcus and others);
- Gram-negative microorganisms (enterobacteria, Escherichia coli, Shigella and others);
- some other types of pathogenic bacterial flora (anaerobes, mycoplasma, and so on).
If you carefully read the instructions, there it is indicated which group Ciprofloxacin belongs to – fluoroquinolones, substances with antimicrobial activity.
Fluoroquinolones inhibit the growth of pathogenic organisms due to disruption in bacteria protein synthesis. Microorganisms lose their ability to reproduce and gradually die due to a violation of protein metabolism.
Although the annotation states that Ciprofloxacin is an antimicrobial agent, it is not effective for all inflammations. The drug has only antibacterial activity and does not affect viruses and fungal spores.
Specified in the annotation characteristic – an antimicrobial drug is misleading a person unfamiliar with the pharmacology. Often you can hear the question when prescribing Ciprofloxacin: it is an antibiotic or antimicrobial agent.
But both of these statements are equally true. Microbes include viruses, bacteria and a number of other microorganisms, and the antimicrobial effect of the drug is spread to pathogens of the bacterial group.
Cipro indications. What does Ciprofloxacin treat?
Dr. Brigitte Mueller-Morel, MD: Ciprofloxacin is prescribed if infectious diseases are caused by bacteria that are susceptible to the drug. The use of the drug has a good effect in various pathologies.
Most respiratory diseases are caused by bacterial flora, so the use of the drug is indicated for the following diseases:
- acute bronchitis;
- exacerbation of chronic bronchitis;
- cystic fibrosis.
In asthma or COPD (chronic obstruction of the lungs), an antibiotic is prescribed, if foreign particles (yellow or greenish) appear in the discharge sputum.
Diseases of ENT organs
The indication for the use of the drug will be:
- frontal disease;
Depending on the severity of the pathology, the drug is prescribed in drops, tablets or injections.
Eye drops are indicated in the following conditions:
- conjunctivitis caused by bacterial microflora;
- corneal ulcers;
- prevention of postoperative complications in the eyeball;
In case of mild diseases and for prophylaxis, only drops are prescribed, and in case of severe infections, additional injections are given or they are recommended to drink pills.
Pathology of the urogenital area
In urology, ciprofloxacin is considered one of the most commonly prescribed drugs. It will help if the patient has detected:
- chlamydia lesion;
- syphilitic chancre;
- gonococcus infection.
The antibiotic is prescribed as monotherapy or in combination with other antibacterial or antiviral agents.
Ciprofloxacin destroys most pathogens of intestinal infections. Its use is effective in the following diseases:
- typhoid fever.
The list of intestinal infectious diseases for which the medicine will help is large.
The medicine helps with the following pathologies:
- intra-abdominal abscess.
These conditions occur when an infectious agent enters the abdominal cavity due to a pathological process or surgical intervention.
To prevent possible postoperative complications, a course of antibiotic therapy is prescribed for prophylaxis.
Pathology of the musculoskeletal system
The medicine will help if a disease of the bone system is accompanied by a bacterial infection.
It is recommended to prescribe Ciprofloxacin if a patient has found:
- septic lesion of bones or cartilage.
Also, the drug is effective in infectious inflammation of the tendons and ligaments.
Damage of the skin and soft tissue
The medication will help if the patient suffers from:
- purulent wounds;
- subcutaneous abscesses;
- infected ulcers;
- pustular rash.
Surface lesions are treated with an ointment, and for deeply located areas of inflammation, tablets or injections are indicated, and in some cases (abscess) antibiotic therapy is prescribed only after opening the pathological center and removing pus.
Despite the activity of the antibiotic against most species of bacteria, sometimes the therapy is ineffective. Most often this is due to the fact that a person, engaged in self-treatment, took the drug uncontrollably and the microflora became insensitive to Ciprofloxacin.
The second reason is that fungi and viruses can cause similar symptoms (pneumocystis pneumonia, viral tonsillitis), and these microorganisms are not destroyed by antibacterial agents. If, within 3 days of treatment, improvement of well-being does not occur, then you should consult with your doctor about changing the medication.
Ciprofloxacin (Cipro) alternatives
Analogs are direct and indirect
Direct Ciprofloxacin alternatives
These are drugs whose active ingredients are ciprofloxacin hydrochloride monohydrate.
From Ciprofloxacin they are distinguished in:
- manufacturing firm;
- release forms;
If the pharmacy does not have Ciprofloxacin (Cipro), then you can buy:
But such a replacement should be done if you cannot buy the drug prescribed by the doctor. The price of Ciprofloxacin tablets is 40-60 dollars (injections are cheaper), so looking for cheap analogues to save a little is pointless.
Indirect Ciprofloxacin (Cipro) analogs
Medicines with a different composition, but with similar bacterial activity, are considered to be indirect analogues. Such a replacement is necessary if the patient has Ciprofloxacin intolerance or if there are other contraindications for using the medication.
To replace the drug, doctors may prescribe:
If a self-replacement of Ciprofloxacin with a structural analog, while respecting the dosage, does not affect the quality of the treatment, then you should consult with your doctor about the use of medicines with a different composition and a similar effect.
When to take Cipro for travelers’ diarrhea?
Spending a holiday in a room with diarrhea is not something that tourists dream about, who spent the whole year saving money for rest. Therefore, prevention of travelers’ diarrhea is so important.
Remember that this disease is caused by microorganisms. Food and drink are polluted with feces. Most often become dirty food, ice and water or drinks.
What products are most dangerous for tourists, as they become sources of infection:
- vegetables and fruits, if they have damaged skin;
- cold snacks;
- fish that is poorly fried;
- milk that is not pasteurized.
Often antibacterial therapy is used to prevent traveler’s diarrhea. This is worth taking care if tourists are going to a country with a low sanitary level, where you cannot get expert help. Chemical prophylaxis should be no more than 30 days. Preparations prescribed by the doctor. But usually 300 mg of Ofloxacin, 400 mg of Norfloxacin, 500 mg of Ciprofloxacin or 500 mg of Levofloxacin are used once a day.
Such prevention is carried out by those who have an immunodeficiency state. It is worth going through to those who are not sure that they will be able to observe personal hygiene or food intake during the trip.
Is Cipro good for tooth infection?
What antibiotics are prescribed by dentists?
Specialists most often appointed antimicrobial antibacterial drugs of a broad spectrum of activity. Very often, antibacterial drugs are prescribed preventively in order to avoid the risk of pyo-inflammatory processes.
There are many drugs that are prescribed for certain cases – all of them do not need to know.
Consider a list of antibiotics used in dentistry for inflammation, which are used most often:
1. Ciprofloxacin (Cipro). It is an antimicrobial medicine with a low allergenicity. Overdose excluded. Contraindicated in pregnant women, children under 18 years of age and patients with various complex diseases. Reception within 4-5 days twice a day after meals. It has a low cost. Often used in the treatment of flux.
2. Augmentin (Amoxiclav). Penicillin group, with antimicrobial action. Since the mid-80s used in medical practice. The main prescribed drug is Amoxiclav 625. Overdose is almost impossible, allowed for nursing mothers and pregnant women.
You can use these penicillin antibiotics in pediatric dentistry. Individual dosages depend on the weight of the person, as well as the need for its use.