Osteomyelitis treatment

Bacterial foot infection. Bone infection treatment antibiotics. Pills Prices

Bacterial foot infection. Bone infection treatment antibiotics. Pills Prices

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Dr. Andreas GrossDr. Andreas Gross (Germany, Hamburg)


Bone infection in toe

Osteomyelitis (Bone infection) is a purulent-necrotic process that occurs in the bone and bone marrow, affecting the surrounding soft tissue. The reason for this pathology is penetration of pus-producing microflora into the body. Often, osteomyelitis in the toes develops as a complication of various bone pathologies, for example, with open fractures.

Bone infection in toe

Acute osteomyelitis begins with a sharp increase in body temperature to 39-40 C. The patient’s condition is deteriorating, due to increasing intoxication of the body. This disease manifests itself with the following symptoms:

  • sharp pain in the foot;
  • chills;
  • headaches;
  • repeated vomiting;
  • sometimes loss of consciousness and delirium;
  • possible jaundice.

In the first few days, there is severe pain in the foot, which can also spread to the lower leg. Painful contractures develop in the affected bones and joints. Active movement with the toes is impossible, while passive movement is severely limited.

Edematous phenomena in the muscles and soft tissues of the foot and lower leg are growing rapidly. The skin above the affected area acquires a purple color and is highly stressed. Often it appears pronounced venous pattern.

When the disease becomes chronic, the patient may feel somewhat better, the pain in the foot decreases, and the pain itself becomes aching. Signs of intoxication disappear, and body temperature returns to normal.

Often, fistulas with scanty purulent secretions form in the affected area. Several such fistulas can form a network of subcutaneous canals, which subsequently open at a great distance from the pathological focus. In the future, there is a persistent stiffness of the joints of the foot and curvature of the bones of the fingers.

How serious is a bone infection?

What is osteomyelitis or bone infection? Is it an inflammatory process of a single bone or a serious illness that can affect the whole body? These questions concern many patients.

How serious is a bone infection

Even after making a diagnosis and receiving a qualified medical consultation, many patients continue to think that osteomyelitis is just a simple inflammation that affects only a small part of the bone, which is rather localized and does not affect other processes in the body at all.

Based on these considerations, many patients do not understand the seriousness of the disease that touched them, which is why they are not serious enough about his treatment, and therefore many times increase the risk of very serious complications that can lead to irreversible consequences and even death.

Therefore, it is necessary to once again focus the patient’s attention on the true state of things and explain to him as much as possible what kind of disease affected his body and what consequences this may have.

For example, it is worth paying special attention to the fact that during the course of this disease the liver and kidneys work noticeably worse, there is a general depletion of the body, the work of the human immune system deteriorates.

Sometimes the cause of death can be not osteomyelitis itself, but diseases that were caused by it, especially in cases where the lesion has overtaken those organs that were already not very healthy at the time of infection with osteomyelitis.

The cause of this disease is staphylococcus – a microbe that causes inflammation of bone tissue, and it is he who is carried by blood, can cause the development of infection in other organs of the body.

Hematogenous osteomyelitis

In hematogenous osteomyelitis, the infection enters the bone marrow along with the flow of blood from another lesion located in the body. The disease can be both acute and chronic. To make an accurate diagnosis necessarily conduct an X-ray examination. At the same time, it can be detected no earlier than the second week.

Hematogenous osteomyelitis

Sometimes treatment begins with antibiotics that lubricate the picture. In this regard, it is desirable not only to make an x-ray, but also to conduct laboratory tests.

Hematogenous osteomyelitis begins with the fact that the place where the affected bone is located swells up. A swelling appears after two or three days after infection in the bone marrow. Particularly valuable such observations may be in the case when the focus of the disease is located in the bones, surrounded by a thick layer of muscle.

With this disease, bone tissue is destroyed at the site of infection. After a week of developing the disease, an x-ray may show a partial onset of osteoporosis. Gradually, the condition of the bone deteriorates, osteosclerosis appears, the destruction of the bone spreads over an increasing area.

The disease can be stopped when therapeutic measures are adequate and started as early as possible. In this case, the bone after some time independently restores its structure. At the same time, hematogenous osteomyelitis usually affects not only the bone itself, but also the soft tissues that surround it. The most difficult process takes place with osteomyelitis in the vertebrae.

Signs of bone infection

For a start, let’s look at more: what is articular infection. The essence of such diseases is that pathogenic microorganisms penetrate into the articulation cavity or the soft tissues surrounding it. They can affect bone tissue, which is a very serious problem.

Signs of bone infection

Symptoms of infection of bones and joints manifest as follows:

  • discomfort in the affected area;
  • increasing pain;
  • local temperature increase, with the spread of infection – general hyperthermia;
  • redness of the skin over the joint;
  • swelling, fluid accumulation;
  • development of necrotic processes;
  • manifestations of intoxication (nausea, general malaise);
  • swollen lymph nodes;
  • impaired motor function;
  • curvature of the articulation.

Bone infection and osteomyelitis causes

Causes and precipitating factors.

The main cause of infectious diseases of the musculoskeletal system are pathogenic microorganisms, in particular, viruses and fungi. The most common provocateur is streptococcus.

What infections affect the joints:

  • streptococci;
  • staphylococcus;
  • salmonella;
  • E. coli;
  • brucella;
  • fungal origin;
  • herpes;
  • pale treponema (syphilis);
  • smallpox viruses, rubella, hepatitis, etc.

They can penetrate into the joint cavity, either directly or indirectly, that is, with the bloodstream in the presence of infection in the body.

The provoking factors of infection with such diseases are:

  • injuries, especially open fractures;
  • stab and gunshot wounds;
  • hypothermia;
  • weakened immunity;
  • surgical interventions;
  • installation of ligatures;
  • infectious diseases of other body systems;
  • inflammatory processes in the surrounding soft tissues.

Bone disorders. Different types of bone infection

Types of bone infection.

On the basis of which infections affect the joints, it is possible to identify the main diseases that occur most often.

1. Small inflammatory forms. This group includes pathologies associated with the formation of small local foci of inflammation. Most often they are provoked by injuries or surgical interventions. For example, an infection of the knee after a fall can lead to an abscess.

2. Tendonitis. Inflammation of the tendons, may cover the area attached to the bone, or to the muscle. A complication may be a rupture or partial tear of the tendon.

Tendinitis pictures, how does it look like?

3. Synovitis. Inflammation of the synovial membrane. Accompanied by increased secretion of synovial fluid, which is expressed in the formation of effusion.

Synovitis pictures

4. Bursitis. Inflammation of the articular bag, with an accumulation of serous or purulent exudate, sometimes with bloody impurities, depending on the type of pathogen.

5. Arthritis. Common name for inflammatory diseases of the joints. It can be as an independent pathology, and accompany other pathologies of the body.

6. Dropsy. Dropsy of the joint is also known as hidrartrosis. As a result of the development of the inflammatory process, fluid accumulates in the cavity of the articular articulation.

7. Rheumatoid arthritis. It is mainly the result of autoimmune disorders in the body, but it is often infections that provoke them.

8. Osteochondrosis. There is a dystrophic change in cartilage tissue, which can also be triggered by the penetration of infection into the joint. The spine is most often affected.

9. Osteomyelitis. Bones and bone marrow are affected, most often under the influence of pyogenic microorganisms, purulent-necrotic destruction of the affected areas occurs.

How to diagnose osteomyelitis?

How to test for osteomyelitis?

When the first symptoms of problems with the musculoskeletal system appear, you should immediately go to the hospital. Only a doctor will be able to establish an accurate diagnosis and prescribe the necessary treatment, which will prevent the development of complications.

How to test for osteomyelitis

To determine which infections affecting the joints are provocateurs of the disease in a particular case, it is necessary to conduct a series of laboratory tests.

These include:

  • general blood analysis (test);
  • blood chemistry test;
  • puncture of the contents of the joint with further bacteriological examination.

Additionally, tests are conducted on the susceptibility of identified microorganisms to certain types of antibiotics.

In order to determine the type of disease, as well as the extent of the spread of the inflammatory process, the patient is assigned additional instrumental studies:

  • ultrasound of the joint;
  • radiography;
  • CT;
  • MRI;
  • scintigraphy;
  • arthroscopy.

The areas of inflammation, especially if purulent accumulations are present, will appear dark on diagnostic images. The most accurate diagnostic method is tomography, as it allows a more detailed examination of the condition of the bone and the soft tissues surrounding it.

Bone infection treatments

Treatment methods for bone infection.

Infectious lesions of the knee joints and other particularly mobile parts of the musculoskeletal system require temporary immobilization. This will reduce pain and swelling, as well as prevent the problem from getting worse.

Instructions regarding further treatment depend on the type of diagnosis that was established during the examination.

Treatment methods for bone infection

For complete therapy, the following directions can be used:

1. Taking medication. Nonsteroidal anti-inflammatory and corticosteroid drugs are required to relieve inflammation. They relieve symptoms and relieve pain. To combat the infection itself, a suitable antibiotic, antiviral or antifungal drug is selected. In the presence of wounds, regular antiseptic treatment is mandatory. Medications are used in the form of tablets, injections, intravenous infusions, as well as in the form of ointments and creams for local effects on the source of the problem.

2. Physiotherapy. After the infection has been eliminated and the inflammation has been removed, one can proceed to carrying out auxiliary therapeutic procedures using special equipment and drugs. The most commonly used electrophoresis, magnetic therapy, UHF, etc.

3. Surgical intervention. Infectious diseases are often accompanied by suppuration and tissue necrosis, which requires reorganization and arthroplasty. In the rehabilitation period, it is important to prevent the reintroduction of pathogenic microorganisms into the wound.

4. Folk remedies. After removing the acute manifestations of inflammation by traditional methods, you can refer to the popular recipes. Their price is minimal, but they can be used to stimulate tissue repair. To strengthen the immunity is recommended to drink herbal decoctions: raspberry leaf, St. John’s wort, chamomile. Apply grated raw potatoes, cabbage leaf, sea buckthorn oil to the sore joint.

5. Special exercises. To restore normal motor ability after the main course of treatment, physical rehabilitation is necessary. To do this, it is recommended to perform special exercises, specially selected for the patient, depending on the state of his health. They strengthen atrophied muscles and ligaments, increase flexibility, stimulate blood circulation and increase the range of motion in the joint. All this is necessary for the full regeneration of tissues.

How to prevent bone infection?

Preventive actions.

Dr. Andreas GrossDr. Andreas Gross (Germany, Hamburg): In order to reduce the likelihood of developing such infectious diseases, it is necessary to pay special attention to their prevention, especially if there is an increased risk of penetration of pathogenic microorganisms.

It is recommended to perform the following activities:

  • protection against overcooling;
  • prevent traumatic injuries;
  • compliance with hygiene standards in the presence of wounds on the body, conducting regular antiseptic treatment;
  • passage of a prophylactic antibacterial course according to the testimony of a doctor;
  • observance of precautionary measures in the rehabilitation period after carrying out surgical interventions, in particular the procedure of osteosynthesis;
  • general strengthening of immunity;
  • timely treatment of colds and other diseases of infectious and viral nature;
  • if an infection was previously detected in the joints, do not tighten with treatment until the pathological process has spread to the bone tissue.

Foot bone problems

Osteomyelitis is an infectious disease that affects the bone marrow and bone. The causative agents of the disease penetrate the bone tissue through the bloodstream or from neighboring organs. The problem of the infectious process may initially occur in the bone when it is damaged due to a gunshot wound or fracture.

This problem was considered incurable before the invention of antibiotics. Modern medicine quite effectively copes with it, using surgical removal of the necrotic part of the bone and a long course of potent antimicrobial agents.

The development of inflammation in the bone substance causes the formation of sequestration – a specific sign of osteomyelitis. This is a dead part, which spontaneously rejects. Vascular thrombosis occurs around the sequestration, blood circulation and bone nutrition are impaired.

Around the sequester accumulate immune cells, forming a granulation shaft. It is manifested by thickening of the periosteum (periostitis). Granulation shaft separates dead tissue from healthy tissue well. Periostitis along with sequesters is a specific sign of osteomyelitis.

What are the problems with bone infection of the foot? Consider some types of bone infection in the legs.

1. Osteomyelitis of the hip. It is observed in people at any age, often has hematogenous origin, but often develops after surgery on the bone. Accompanied by hip swelling, fever and impaired mobility of adjacent joints. A large fistula forms on the skin, through which pus is separated.

Osteomyelitis of the hip

2. Osteomyelitis of the bones of the leg. It is observed more often in adolescents and adults, often complicates the course of leg fractures. Accompanied by redness and swelling of the leg, severe pain, the formation of fistulous passages with purulent discharge. First, the tibia bone is affected, but then the fibular is always inflamed. The patient cannot step on the foot.

Osteomyelitis of the bones of the leg

3. Osteomyelitis of the calcaneus. In contrast to the forms described above, this infection usually has a long course and often complicates infectious diseases of the foot, for example, in diabetes. The main symptoms are soreness and swelling in the heel, redness of the skin, ulceration with discharge of purulent contents. The patient can hardly move, leaning on the front of the foot.

4. Osteomyelitis of the metatarsal bone. It develops with insufficiently careful surgical treatment of wounds resulting from injured foot. It can also complicate the course of diabetes. Accompanied by pain and swelling of the foot, difficulty in walking.

Osteomyelitis of the metatarsal bone

Symptoms of bone infection in leg

Symptoms of osteomyelitis are bones in the leg.

Signs of foot osteomyelitis:

  • fever and chills;
  • bone pain;
  • swelling of the lesion;
  • impaired function of the affected limb – the inability to step on the affected leg;
  • formation of fistulas – holes in the skin through which pus is secreted;
  • feeling unwell, in children – irritability or drowsiness.

Sometimes the disease is almost without external manifestations.

Seek medical attention for a combination of fever and pain in one or more of the bones of the legs.

The physician must conduct a differential diagnosis with such diseases:

  • rheumatoid arthritis;
  • infectious arthritis;
  • synovitis;
  • intermuscular hematoma, including suppurative;
  • bone fracture.

Treatment for bone infection in foot. How to cure osteomyelitis?

Modern approaches to therapy

Therapeutic tactics depend on the following circumstances: the etiology of the process, the pathogenicity of the isolated pathogen and its resistance to therapy, the age of the patient, concomitant diseases and the presence of complications.

Conservative osteomyelitis treatment

Therapy should be combined: medication, surgical care, physiotherapy and other auxiliary methods.

Conservative osteomyelitis treatment

In any case, the patient is hospitalized, undergoes thorough examination and is under medical supervision throughout the treatment process. It is mandatory to immobilize the limb.

Dr. Andreas GrossDr. Andreas Gross (Germany, Hamburg): After isolating the pathogen and checking the resistance of the microbe to prescribed drugs, antibiotic therapy is applied. Priority is given to drugs capable of penetrating bone tissue. Clindamycin (Cleocin), Fusidin, Ceftriaxone, Lincomycin, Vancomycin are often used.

Clindamycin (Cleocin) antibiotic for osteomyelitis treatment

Depending on the severity of the condition, the agents are injected intramuscularly, intravenously and into the medullary canal. As a rule, treatment courses last at least 30–45 days, often with a change of drugs.

If the application of surgical methods is impossible due to the state of health, antibacterial therapy is carried out with short periods of rest and continues until the end of the patient’s life.

In addition to the use of antibiotics, intensive infusion therapy is needed with intravenous administration of Hemodez, Reopolyglucin, Albumin solutions.

Also, doctors prescribe drugs from the following pharmacological groups:

  • antiseptics – for local treatment and intraosseous administration;
  • anesthetics – to relieve pain;
  • nonsteroidal anti-inflammatory drugs (Diclofenac, Movalis);
  • hyposensitizing drugs (Pipolphen);
  • immunomodulators, including specific immunoglobulins.

In preparation for the operation and after it, physiotherapy is performed. In the recovery period, therapeutic physical training is needed.

Can I take antibiotics for arthritis and arthrosis?

There are certain types of joint diseases that involve antimicrobial treatment. This group includes septic (purulent) arthritis, in which the pathogens penetrate the joint and cause various pathologies. This also includes inflammatory arthritis, infectious, allergic, reactive. With this diagnosis, the disease of cartilage can not only accelerate its development, but also cause the flu, Lyme disease, acute intestinal infections. Here, without antibiotics cannot do. In other cases, antimicrobial treatment is not provided.

What are the most effective antibiotics for bone infection?

In most cases, when a person comes to a doctor for help, arthritis makes itself felt as much as possible and is accompanied by severe pain. Therefore, it is very important to establish a diagnosis in a short time and select effective drugs for treatment. However, it is not so easy to instantly improve the condition of the patient, since it is necessary to observe the reaction of his body to this or that medicine.

The doctor selects an antibiotic based on the possible ways through which the infection could get into the joint. For example:

1. Infection has penetrated the joint as a result of urogenital diseases. In this case, selected drugs related to the tetracycline series. Among these drugs, the following are widely known: Tetracycline, Doxycycline, Oxytetracycline, Methacycline, Minocycline. Additionally, prescribed drugs with fluoroquinolone (Lomefloxacin, Ofloxacin) or macrolide (Erythromycin, Azithromycin, Roxithromycin). These drugs block the synthesis of proteins in bacterial cells.

effective antibiotics for bone infection

2. If the patient is suffering from a disease of the joints parallel sick upper respiratory tract infections, then he is likely to appoint agents with semi-synthetic penicillins (Amoxicillin, Ampicillin, Carbenicillin), cephalosporins (Cefazolin, Cefotaxime) or macrolides (Erythromycin, Roxithromycin). These drugs are able to eliminate the resulting cell network of bacteria, gradually destroying them completely. Well tolerated by the human body, have a minimum of side effects.

bone infection antibiotics

3. In the event of an intestinal lesion by infection, drugs containing fluoroquinolones (Ofloxacin, Lomefloxacin, Sparfloxacin) are prescribed. They have a wide spectrum of action, destroy the DNA metabolism of bacteria.

How to treat reactive arthritis with antibiotics?

In order for antimicrobial therapy to be effective, it must be supplemented with anti-inflammatory, analgesic and regenerating drugs. The duration of complex treatment can last up to several months, but this does not apply to antibiotics.

During the post-infection period of the patient (for example, he suffered a severe purulent tonsillitis), antibiotics can also be administered, in parallel with rheumatoid drugs to completely destroy the site of infection.

Check out the reactive arthritis antimicrobial regimen:

  • Azithromycin – taken once a pill and is valid for a week.
  • Doxycycline tablets – prescribed one twice a week, every day.
  • The course of treatment usually lasts up to 7 days.
  • If the inflammatory focus is not eliminated, then another antibiotic complex is prescribed, for example, Erythromycin or Ofloxacin.
  • In addition, treatment can be strengthened by the appointment of Amoxicillin, two tablets three times a day, to drink for a week.

Antibiotics of all groups, one way or another, affect the human body, so side effects are inevitable. Many drugs have their own substitutes and vary in intensity of exposure to the human body. Some patients have individual intolerance or sensitivity to individual components of drugs – this should also be considered during the treatment of arthrosis or arthritis with antibiotics.

Consider the following examples of side effects on specific drugs:

  • The action, for example, of Erythromycin is less effective with Azithromycin, and the effect on the digestive system often leads to a forced rejection of its use. If you do not want to refuse, try to combine its reception with probiotics.
  • Roxithromycin with Clarithromycin is rapidly excreted from the body, therefore, have less pronounced side effects. Often patients opt for these drugs.
  • Pregnant women should refuse treatment with Ofloxacin or Doxycycline.
  • In the main part, antibiotics lower the level of the body’s immunity, thereby reducing the ability to resist various infections.
  • Some strong-acting drugs can cause problems with the blood circulation and nervous system processes.

Best antibiotic for bone infection and joint damage

Given the nature of the inflammatory process, the doctor selects a course of treatment. If autoimmune reactions are the cause of inflammation, antimicrobial drugs are not used. In case of joint damage due to infection of the body, broad-spectrum antibiotics are recommended.

Antibacterial pills do not eliminate the symptoms of acute inflammation and do not remove the pain syndrome. The action of these drugs is aimed at:

  • favorable prognosis of treatment;
  • prevention of relapses;
  • increase in the period of remission.

If the doctors have not determined the cause of the disease of the legs, the patient is prescribed a course of antibiotic therapy. These repairs are canceled after an accurate diagnosis.

The course of antibiotic therapy is 7 days. The dosage is set individually depending on the degree of development of the lesion. Simultaneously with antibiotics for arthritis and arthrosis, they take medications aimed at eliminating the negative effects of the components of antimicrobial drugs.

Antibiotics for arthritis and arthrosis are chosen based on the method of infection penetration into the body, the sensitivity of the causative agent of the pathology to the active substances of medicines.

We indicate antibiotics for arthritis and arthrosis, which are used depending on the method of infection:

  • 1. Fluoroquinolones, tetracyclines, macrolides. Drugs from these groups are used in penetrating the urinary tract infection. The most commonly prescribed Tetracycline, Doxycycline, Azithromycin, Minocycline.
  • 2. Medicines of penicillin, macrolide, cephalosporin series. They are prescribed when the upper respiratory tract enters the cause of infection. The most popular are Erythromycin, Amoxicillin, Cefotaxime, Ampicillin, Roxithromycin, Cefazolin.
  • 3. Fluoroquinolones. Used for infection through the digestive system. Ciprofloxacin, Ofloxacin, Sparfloxacin may be prescribed from this group.

How to treat arthritis and arthrosis with antibiotics? Treatment regimen

For the treatment of arthritis and arthrosis, in addition to antimicrobial agents, the doctor prescribes revitalizing, anti-inflammatory, anesthetic drugs. Comprehensive treatment lasts up to several months. Antimicrobial tablets are recommended to be used for the destruction of the source of infection for 1 week in conjunction with rheumatoid drugs.

Rheumatologists can offer this antibiotic regimen:

  • Azithromycin. Take the drug once, the action lasts a week.
  • Doxycycline. Used in pill form. Recommended for use twice a day, one tablet. Take the medicine daily.
  • Erythromycin, Ofloxacin. The complex of these drugs is prescribed when it is impossible to eliminate the focus of inflammation.
  • Amoxicillin. This drug is prescribed to strengthen therapy. Take 2 tablets at a time. Three medications per day for a week.

The best antibiotics for treating rheumatoid arthritis

In the basic therapy of rheumatoid arthritis, antibiotics are used. The basis of the basic treatment is the use of biologically active disease-modifying agents.

Experts are use:

  • Cytostatics: Cyclophosphamide, Azathioprine, Consupren.
  • Antimalarial drugs. They are used for six months. This is due to the fact that antimalarial drugs have a slow effect. From this group, doctors prescribe Immard, Plaquenil, Delagil.
  • Preparations from the class of sulfonamides (Sulfasalazine). The duration of the therapeutic course may be a year.
  • Penicillins (Tauredon, Cuprenyl, Crysanolum). Tablets of this class are prescribed in the case when other medicines from the basic therapy are ineffective.

Antibiotics for inflammation and infection of the joints

Drugs are selected taking into account the trigger infection, which caused damage to the joints.

1. Tetracyclines

The most reasonable will be the appointment of tetracycline drugs (drug tetracycline). They have a high activity against chlamydial and enterococcus flora, are well distributed in bone tissue.

Tetracycline antibiotics in the treatment of rheumatoid arthritis are not etiotropic therapy. However, the use of drugs Tetracycline and Doxycycline (200 mg twice a day) reduces the activity of cartilage-damaging enzymes, slows down degenerative processes in the joint, reduces edema, and reduces pain.

2. Sulfonamides

However, the effect of taking Sulfasalazine is practically not inferior to the action of cytostatics, which allows using this drug in basic therapy of rheumatoid arthritis, especially if there are contraindications to the use of Methotrexate.

Sulfasalazine has:

  • pronounced antimicrobial activity;
  • anti-inflammatory action.

The drug is well distributed in the body, penetrates through tissue barriers, accumulates in the connective tissue and synovial (articular) fluid.

Features of use and side effects.

When conducting therapy with sulfonamides recommended to avoid ultraviolet radiation. It is also necessary to ensure an adequate drinking regime (at least two liters of water per day).

These antibiotics for bones and joints are not used in pregnant women, as a result of teratogenic effects on the fetus. Prohibited to receive during lactation. They penetrate into breast milk, provoke nuclear jaundice and hemolytic anemia of newborns.

Antibiotics for chlamydial arthritis

For the treatment of arthritis of chlamydial etiology, the use of macrolides in daily dosages is effective.

Antibiotics for arthritis tablets:

  • Azithromycin: 500-1000 mg.
  • Roxithromycin: 300 mg.
  • Clarithromycin: 500 mg.

With prolonged use of Erythromycin, jaundice may appear, as a result of the development of cholestatic hepatitis. Characteristic appearance: abdominal pain, yellowness of the skin and mucous membranes, pronounced itching, increased liver transaminases in the biochemical analysis of blood.

Rarely, the administration of high doses of Clarithromycin in patients with renal insufficiency leads to reversible hearing impairment.

Roxithromycin is contraindicated during pregnancy. It is permissible, with caution, to use Clarithromycin and Azithromycin (strictly under the supervision of a specialist).

Oral antibiotics for osteomyelitis. How to treat osteomyelitis?

Treatment of osteomyelitis with antibiotics is carried out in all cases. Bone disease is caused by the activity of bacteria against which only this group of drugs is active.

If post-traumatic osteomyelitis, that is, it arose after receiving a bone injury, then surgical treatment may be prescribed. In this case, antibiotics are prescribed to the patient before the intervention and after the manipulation.

The operation in the outbreak of inflammation can also be carried out with hematogenous osteomyelitis of the bone. In this form of pathology, the pathogen penetrates into the bone tissue with blood flow. To destroy the bacteria, in addition to local treatment, antibiotics are required.

The order of appointment of antibiotics

Antibiotics for osteomyelitis in children and adults are prescribed only by the attending physician. To select an effective drug, laboratory tests are conducted.

The doctor must find out what kind of bacteria caused the development of the disease in the bone. Before choosing a type of antibiotic, it is worth considering the possible development of allergic reactions in a patient and the sensitivity of microorganisms to the main active ingredient.

If antibacterial agents have already been applied, it is important to find out whether the pathogens have developed resistance to the drug.

After receiving the results of sowing, the drug is prescribed. Treatment begins with maximum doses.

The course of treatment is usually 4-6 weeks, depending on the patient’s condition and the stage of development of the pathology. In the first days of the acute process, injections are performed every 4 hours. After completion of the intravenous administration of the drug, another 2 weeks should be taken with the antibiotic in pills.

Important! Sometimes a doctor may prescribe an antibiotic pill. This is possible provided the choice of tools that penetrate well into the bone and can stop the infectious process.

What drugs are used to treat osteomyelitis? The best antibiotics

Antibiotic for the treatment of osteomyelitis of the bone is selected based on the type of pathology and infectious pathogen. First, a drug is prescribed that affects a wide group of cocci and anaerobic bacteria. Allows a sequential transition from intravenous administration to taking pills.

For osteomyelitis, the following medications are most often used:

  • Ciprofloxacin;
  • Ofloxacin;
  • Vancomycin;
  • Ceftriaxone;
  • Clindamycin.

In severe osteomyelitis in children, several antibacterial drugs can be prescribed to fight infection. In no case cannot independently replace drugs similar in composition or action.

Bone infection antibiotics price. Where to buy antibiotics without prescription and insurance?

You can buy antibiotics for the treatment of bone infections in the city pharmacy, as well as in the Internet pharmacy. The purchase of drugs in the online pharmacy is carried out without a prescription and is completely anonymous. Health insurance is also not required.

Below we give the prices of the main antibiotics described in this article. These prices are relevant in most online pharmacies.

Doxycycline 100 mg

30 pills – $36;

90 pills – $51;

360 pills – $121.

Zithromax 500/250/100 mg

30 pills – $74/ $46;

90 pills – $134/ $94/$54;

360 pills – $402/ $307/ $156.

Ciprofloxacin (Cipro) 750/500/250 mg

30 pills – $60;

90 pills – $116/ $51/ $40;

360 pills – $365/ $119/ $89.

Amoxicillin 500/250 mg

30 pills – $33;

90 pills – $64/ $47;

360 pills – $201/ $158.

Tetracycline 500/250 mg

60 pills – $43;

90 pills – $58/ $34;

360 pills – $194/ $111;

Ampicillin 500/250 mg

60 pills – $31;

120 pills – $55/$33;

360 pills – $150/$89.

We have indicated not all antibiotics available in pharmacies and their prices. For more information about prices, dosages and availability of drugs, you need to visit the official website of the online pharmacy.

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