Drug Sildenafil for Male Potency

The Effectiveness of the drug Sildenafil for Male Potency

The Effectiveness of the drug Sildenafil for Male Potency

With sexual dysfunction and a weak erection, the drug Sildenafil is often used. Its action is based on stimulation of blood circulation in the organs of the small pelvis, due to which the potency increases, the time of sexual intercourse prolongs.

Sildenafil has many analogues, starting from the well-known “Viagra”. How often you can take the drug “Sildenafil”, reviews, instructions and the price of this tool is discussed in detail in our article.

Composition and description of the preparation

The main active substance of the drug is Sildenafil Citrate. In terms of Sildenafil, the dosage is 25, 50 and 100 mg. In addition, the composition has auxiliary substances: microcrystalline cellulose, aluminum hydroxide, magnesium stearate, sodium croscarmellose and dyes.

Dosage form of sildenafil

Sildenafil is available in the form of biconvex tablets, coated with a shell. The color of the shell varies from pale blue to blue, pearl and marble effect is allowed. Tablets of small size, round or diamond-shaped, packed in 1, 2 or 4 pieces in a package.

Dosage is from 25 to 100 mg, but there are drugs with an increased concentration of up to 150 mg. Take them only if prescribed by a doctor. In the course of a clinical study, a safe daily dosage of sildenafil is set at 100 mg.

Avaliable Sildenafil dosages is from 25 to 100 mg

Pharmacologic effect

The drug is used to improve erectile function. Accepted orally, refers to inhibitors of cGMP-specific phosphodiesterase in cavernous bodies. The mechanism of action is the activation of the enzyme due to the release of nitric oxide during sexual stimulation. Sildenafil tablets exert a powerful relaxing effect on isolated human cavernous bodies. The effect of the drug has a peripheral effect.

Pharmacodynamics of Sildenafil is an elective action, so for the impact requires a natural sexual arousal. The active substance has a strong effect, helping to relax the muscles of smooth muscles, increase blood supply and vasodilation in the genital. Metabolized in the liver, excreted mainly with feces and urine.

The history of the creation of tablets Sildenafil

Initially, the effect and pharmacodynamics of sildenafil on the stimulation of blood flow in the myocardium was studied. The drug was synthesized to create effective drugs against coronary heart disease, but his actions were not enough. In the course of the research, “side effects” of increasing the blood supply to the pelvic organs were revealed, due to which the development changed orientation, it became possible to study the possibility of using the means for improving potency and treating erectile dysfunction.

In the US, Sildenafil is available under the Viagra brand of Pfizer. Thus, this is the same drug whose composition and pharmacodynamics are identical. Developments were carried out relatively recently – in 1992, but the brand very quickly became recognizable and in demand all over the world.

Pfizer commercialized Sildenafil as an erectile dysfunction treatment

Now Sildenafil has many analogues, many similar drugs use other mechanisms of action and active substances, but, and the name “Viagra” has become a household name.

Indications for use

The drug is used for physiological disorders of erectile function. Activation of the inhibitor occurs with sexual stimulation, and the drug itself does not affect this function, but only increases the relaxation of the smooth muscles of the penis, which improves blood flow and there is a persistent erection.

Most often, the drug is used to treat:

  • Erectile disorders of various etiologies;
  • Sexual dysfunction at different ages;
  • In complex therapy of impotence;
  • In the treatment of pulmonary hypertension.

The treatment regimen and additional medication should be agreed with the attending physician. Usually, the remedy is applied as needed, and not on a regular basis. Due to the selective effect, the drug does not require correction in diagnosed renal or hepatic insufficiency. However, the combination of certain drugs can reduce or increase the effect of taking Sildenafil, so it is worth getting the doctor’s advice before taking.

Drug interaction

The drug cannot be taken with other products containing nitrates in any form. Simultaneous reception of enterosorbents reduces absorption, like fatty foods.

It is not recommended to mix tablets with alcohol – the risk of side effects and individual sensitivity is great.

Sildenafil and alcohol are not recommended together

Concentration in the blood increases with simultaneous reception with:

  • Cimetidine;
  • Erythromycin;
  • Ketoconazole;
  • Calcium antagonists;
  • Beta-blockers;
  • Hypoglycemic drugs.

Due to the vasodilating effect, it is possible to lower blood pressure, so patients with hypotension need additional advice from the doctor before admission.

At the age of 65 years, the effect of the drug may not be expressed so much, besides, with existing problems with cardiac activity, it is also necessary to weigh the pros and cons before prescribing Sildenafil.

How long does Sildenafil last?

The drug is administered orally, about an hour before sexual intercourse. The drug lasts about five hours, but only on condition of sexual arousal. Single dose is 50 mg. The maximum daily dose is 100 mg. If necessary, the agent is used in a dosage of 25 mg.

A great advantage of using the drug is the lack of addiction.

Thus, the effect of the drug does not decrease with time and can be used in a long period.

Contraindications for the use of Sildenafil

Not always the benefit of the drug will be justified. Due to the content of nitric oxide, simultaneous reception with similar means is forbidden. For example, when using products containing nitric oxide or nitrates in any form.

In addition, the use of funds is prohibited in the following cases:

  • Hypersensitivity to the components of the drug;
  • Diseases of the cardiovascular system;
  • Sickle-cell anemia;
  • Leukemia;
  • Violations of the function of blood flow;
  • Childhood;
  • Multiple myeloma;
  • Deformations of the penis with impaired blood supply.

Who should not take sildenafil

When using, always consult a doctor to avoid the risk of side effects and contraindications. This is especially important in the elderly, when an increased load can provoke problems of the cardiovascular system.

Side effects

In the absence of medical contraindications, the drug is usually well tolerated. However, side effects are possible, which are manifested in the form of headaches, redness of the face and a feeling of hot flushes. There may be general malaise, nasal congestion. Sometimes – disorders of the digestive function, photosensitivity. Due to the stimulation of blood circulation and the production of the hormone cGMP-specific phosphodiesterase, visual impairments, a decrease in the sensitivity of the color of the objects (blue and green hues), and an increased negative reaction to light are possible.

If such symptoms appear, you should stop taking the medication, and contact your doctor to agree a replacement for the drug.

If negative reactions are manifested too much, you can take enterosorbent and antihistamine, and also go to the hospital for gastric lavage and reception of stabilizing agents.

Reviews of Sildenafil

Comments of men about Sildenafil intake are mostly positive. The drug helps to strengthen the erection and prolong the time of sexual intercourse, as well as normalize sexual function.

The effect lasts up to five hours, and regular use retains a positive effect, helping to maintain a full sexual life without additional stimulation.

Negative reviews of Sildenafil mostly refer to uncomfortable sensations that may occur after using the drug. The most frequent complaints are dizziness, noise in the ears and a rush of blood to the face.

Side effects are exacerbated by the simultaneous intake of alcoholic beverages, with which the tablets are completely incompatible. How often you can take sildenafil depends on the individual characteristics of the body, but if side effects occur quite often, you should consult a doctor to choose a more suitable analogue.

Popular analogs

The active substance sildenafil is a part of many drugs of a similar effect. The patented trademark is Viagra, but there are many similar products.

Analogs for the active ingredient:

  • Aurogra;
  • Caverta;
  • Fildena;
  • Kamagra;
  • Female Viagra;
  • Lady Era;
  • Nizagara;
  • Penegra;
  • Revatio;
  • Silagra;
  • Sildigra.

Sildenafil popular analogs

In comparison with the analogue, “Sildenafil” has a very reasonable price. This is due to the fact that the release of the drug is established in India, which means that it refers to the so-called generics. They are characterized by a large number of side effects, rather than the original products. That is why, the consequences of taking Sildenafil in some cases may be unpredictable. However, if there are no medical contraindications, and the dosage is strictly observed, the risk of side effects is minimal. That is why, many urologists prescribe this remedy for the treatment of impotence in men with less financial costs.

What is the difference between Sildenafil and Viagra?

In the pharmaceutical market, Viagra appeared relatively recently, but the popularity of this drug to increase potency has long been a household name. The developers gave men a unique opportunity to strengthen and normalize their sexual function at almost any age. For young men, it will help to strengthen sexual desire and prolong sex, and for the older age group – to return the possibility of a full sexual intercourse.

The original tool is expensive, so most consumers of Viagra is unavailable, especially for permanent use.

A special feature of patenting medicines is the short duration of the protection of the original drug. Usually, the patent is valid for 5-10 years, after which any pharmaceutical company can produce its own operating time on the basis of substances and chemical compounds specified in the original composition. Of course, such drugs are issued under a different trade name and do not have the right to refer to the original brand for the promotion of their goods.

Difference between Sildenafil and Viagra

At the same time, this practice gives us more chances as buyers, for the purchase of an inexpensive analog. In many countries, the technique of prescribing drugs for the active ingredient and dosage is common, so it is possible to buy similar drugs at a more affordable price. At us this “function” is usually performed by the pharmacist in the pharmacy, which at the request of the patient can offer an analogue of the prescription in its absence, or an overcharge. Of course, this approach is somewhat wrong, but the above-described drugs contain an absolutely identical active substance in the composition, and in the same dosage. The difference is represented by additional substances, as well as the way of manufacturing and cleaning the components.

Thus, the notorious “Viagra” has the same effect on the male body as Sildenafil and the preparations containing it. According to the opinions of patients and doctors who prescribe this remedy, different reactions can occur for different types of medications, but there is also a certain psychological effect. The use of sildenafil is not so effective if the patient purchased it instead of the “Viagra”, although the pharmacokinetics of both drugs is completely identical.

Comparison of Sildenafil with popular analogs

In addition to “Viagra”, the drug has many more varieties, which also contain the active ingredient sildenafil. In addition, there are indirect analogues of the remedy, whose action is also to stimulate the blood supply of the genital organs, but with the help of other active substances. The most famous in this group are Vardenafil and Tadalafil. All three active components are used to increase the erectile function in men, according to reviews, have approximately the same effect, but they also have some differences.

Comparison of sildenafil with popular analogs

In addition to “Viagra”, the drug has many more varieties, which also contain the active ingredient sildenafil. In addition, there are indirect analogues of the remedy, whose action is also to stimulate the blood supply of the genital organs, but with the help of other active substances. The most famous in this group are Vardenafil and Tadalafil. All three active components are used to increase the erectile function in men, according to reviews, have approximately the same effect, but they also have some differences.

Comparative characteristics:

1. Vardenafil or Sildenafil, which is better? Compared with Vardenafil, the second drug is more studied and tested. At the same time, both drugs cause a strong and prolonged erection and allow prolonging sexual intercourse with proper psychological stimulation. The exposure period is approximately the same, and the use of Vardenafil is manifested with a lower risk of side effects. The difference can be found in the full compatibility of Vardenafil with alcohol, as well as with a more aggressive effect, because the erection comes in 15-20 minutes after taking the remedy.

2. Tadalafil or Sildenafil, which is better? Both drugs are sufficiently tested and have the same time of onset of effect and contraindications. The difference is the duration of the action. Sildenafil is about five hours, while Tadalafil differs as much as possible among such drugs effect – up to 36 hours. In addition, in small quantities, Tadalafil is compatible with alcoholic beverages, while Sildenafil and alcohol demonstrate complete incompatibility. The incidence of side effects in Sildenafil is slightly higher, so in this regard, preferences are not on his side.

3. Silagra or Sildenafil, which is better? The composition and pharmacokinetics of both drugs are almost identical. The main active ingredient is sildenafil, but the “Silagra” means more convenient dosages. The list of contraindications and side effects they have is the same, and the cost differs slightly, depending on the manufacturer.

Modern drugs that stimulate sexual function in men are diverse, but only three active substances are taken as a basis for each. This is Sildenafil (the trademark “Viagra”), Tadalafil (“Cialis”) and Vardenafil (“Levitra”). The latter substance was synthesized relatively recently, in 2005, it has a strong effect and a minimal amount of side effects.

Among the advantages of Tadalafil – a long-lasting effect, which is 36 hours. If such an action is necessary, the best choice will be the preparations of this group. On the sildenafil side is a sufficiently studied effect and positive use reviews throughout the world. Ideal means, however, does not exist, so everyone should choose a drug according to individual preferences and quality of portability.

Storage conditions and shelf life of the drug

The preparation is packed in standard plastic blisters; the outer box is made of cardboard. There are different dosages and equipment. Usually it is 1, 2 or 4 tablets, but there is a packing and more. Keep away from direct sunlight in a cool place (temperature not above +25 degrees) and protected from children. Shelf life is 2 years after manufacturing.

Sildenafil tablets, the instruction and feedback about which are given in our information, are often used in the treatment of erectile dysfunction. They help to normalize the circulation of the penis, strengthen the erection and prolong sexual intercourse. Are applied as necessary on the calculated dosage.

The agent has the least possible side effects and can be used for a long period without reducing effectiveness.

The main active substance is used in the manufacture of all known “Viagra”, and, according to reviews, “works” is not worse. Features of the reception, pharmacological action and the like are discussed in our article.